Family name Holguin Pilligua (Holguin Pilligua 
) , in the entire world, is a rare last name. The surname Holguin Pilligua is characteristic of Latin America and the Caribbean, particularly Ecuador, where it is quite a rare surname.
| VARIANT | COUNTRY |
|---|---|
| Holguin Pilligua | Ecuador |
Sixto Alfredo, Cesar Tomas, Jorge Luis, Elsa Maria, Emma Rosaura, Sixto Armando, Carmelo Guillermo, Jose Enrique, Maria Adriana, Domingo Wiltong, Johanna Maribel, Cristian Javier, and Felix Maximino